PGT – Preimplantation Genetic Testing
Genetic testing of embryos during IVF to help guide embryo selection before transfer.
Purpose
PGT is performed during IVF to help identify embryos that are more likely to result in a healthy pregnancy. It is used to support embryo selection in specific situations such as recurrent pregnancy loss, advanced maternal age, or known genetic conditions.
Types:
PGT-A: Detects chromosomal abnormalities (aneuploidy)- PGT-M: Detects specific genetic disorders in embryos
- PGT-SR: Detects structural chromosomal rearrangements
Benefits and Evidence
Benefits
Reduces miscarriage risk, increases live birth chance, and helps prevent transmission of certain genetic disorders.
Evidence
WHO and ASRM recommend PGT in couples with recurrent pregnancy loss, advanced maternal age, or known genetic disorders.
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